smoke: Small Molecule Octet/BLI Kinetics Experiment

Bio-Layer Interferometry (BLI) is a technology to determine the binding kinetics between biomolecules. BLI signals are small and noisy when small molecules are investigated as ligands (analytes). We develop this package to process and analyze the BLI data acquired on Octet Red96 from Fortebio more accurately. Sun Q., Li X., et al (2020) <doi:10.1038/s41467-019-14238-3>. In this new version, we organize the BLI experiment data and analysis methods into a S4 class with self-explaining structure.

Version: 2.0.1
Depends: R (≥ 3.5.0), methods, graphics, grDevices, stats, utils
Imports: Rdpack
Published: 2024-03-10
DOI: 10.32614/CRAN.package.smoke
Author: Qingan Sun, Xiaojun Li, James C Sacchettini
Maintainer: Qingan Sun <quinsun at>
License: GPL-2 | GPL-3
NeedsCompilation: no
CRAN checks: smoke results


Reference manual: smoke.pdf


Package source: smoke_2.0.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): smoke_2.0.1.tgz, r-oldrel (arm64): smoke_2.0.1.tgz, r-release (x86_64): smoke_2.0.1.tgz, r-oldrel (x86_64): smoke_2.0.1.tgz
Old sources: smoke archive


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